LabWAS
Flagship Project LabWAS The goal of the LabWAS workgroup is to leverage clinical lab tests stored in EHRs to understand the relationship between genetic risk for psychiatric disorders and quantitative...
View ArticleThe study of opioid use disorders in a biobank setting
Flagship Project The study of opioid use disorders in a biobank setting The Opioid Use Disorder workgroup aims to study the genetics of opioid use disorders (OUD) using electronic health record data...
View ArticlePsycheMERGE Diversity Initiative
Flagship Project PsycheMERGE Diversity Initiative The availability of large-scale biobanks linking electronic health records (EHRs) to biospecimens has created a powerful opportunity for increasing...
View ArticlePrecision Medicine Approach in Psychiatry based on Individual Imputation of...
Flagship Project Towards a Precision Medicine Approach in Psychiatry based on Individual Imputation of Genomic Features The goal is to impute genomic features (e.g. gene/isoform expression, histone...
View ArticleMeta-analysis of developmental language disorder cases from electronic health...
Flagship Project Meta-analysis of developmental language disorder cases from electronic health records Developmental language disorder (DLD) is a common pediatric language impairment that affects up...
View ArticleEpidemiology and genetics of trauma and posttraumatic stress outcomes in...
Flagship Project Epidemiology and genetics of trauma and posttraumatic stress outcomes in electronic health records Posttraumatic stress disorder (PTSD) is the sentinel psychiatric disorder following...
View ArticleExamining the relationship between year of birth and polygenic risk scores
Flagship Project Examining the relationship between year of birth and polygenic risk scores Polygenic risk scores (PRS) are already being used in the clinical context (e.g., cancer genetics) and they...
View ArticleFunctional Seizures (FS)
Flagship Project Functional Seizures (FS) Functional seizures (FS) are severely understudied paroxysmal episodes clinically similar to epileptic seizures but without aberrant brain electrical...
View ArticlePhenome Wide Association study (PheWAS) of ADHD and Autism
Flagship Project Phenome Wide Association study (PheWAS) of ADHD and Autism Studies have indicated that Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorders(ASD) are...
View ArticleSubstance use disorders genetics
Flagship Project Substance Use Disorders Genetics We have explored the polygenic contributions of substance use disorders (alcohol, cannabis) across multiple medical phenotypes. Our primary site has...
View Article